Researchers turned programmable proteins into a novel genetic tool, potentially enabling tighter control of gene expression. LacI is a tetrameric protein, using two dimers to bind two specific, ...
A modular genetic switch that tightly regulates gene expression in mammalian cells will be useful in the design of complex synthetic gene circuits. One of the goals of synthetic biology is the ...
Scientists have been trying to understand the nature and importance of protein-DNA interactions since the early 1960s. Such research started with studies of the association of RNA polymerase with DNA, ...
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