RNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA ...

Researchers developed DoriVac, a DNA origami-based vaccine platform that precisely arranges antigens and adjuvants to enhance ...

A dissertation study at the University of Jyväskylä (Finland) developed two-dimensional fishnet-like structures from DNA origami for silicon surfaces and investigated how different conditions affect ...

Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.

Essentially DNA origami enables long strands of DNA to fold, through self-assembly, into any desired shape. (In the 2006 paper, Rothemund famously used the technique to create miniature DNA smiley ...

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...

DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

Chemotherapy is the primary cancer treatment used today. It involves using cytotoxic agents which attack and kill cells that are rapidly dividing, like cancer cells. However, delivering these drugs ...

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...

A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.